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W David Merryman Selected Research

5-HT2B Serotonin Receptor

1/2021Targeting 5-HT2B Receptor Signaling Prevents Border Zone Expansion and Improves Microstructural Remodeling After Myocardial Infarction.
1/2020Genetic ablation of serotonin receptor 2B improves aortic valve hemodynamics of Notch1 heterozygous mice in a high-cholesterol diet model.
12/2018Bone Marrow-Derived Proangiogenic Cells Mediate Pulmonary Arteriole Stiffening via Serotonin 2B Receptor Dependent Mechanism.
1/2016Serotonin 2B Receptor Antagonism Prevents Heritable Pulmonary Arterial Hypertension.

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W David Merryman Research Topics

Disease

9Aortic Valve Disease
01/2021 - 04/2014
7Fibrosis (Cirrhosis)
01/2022 - 11/2011
4Heart Diseases (Heart Disease)
01/2022 - 05/2015
3Aortic Valve Stenosis (Aortic Stenosis)
01/2022 - 04/2019
2Hypertrophy
01/2022 - 01/2022
2Myocardial Infarction
01/2021 - 01/2019
2Carcinoid Tumor (Carcinoid)
01/2020 - 11/2011
2Mitral Valve Prolapse
03/2014 - 09/2012
1Hypertension (High Blood Pressure)
01/2022
1Osteoporosis
01/2022
1Postmenopausal Osteoporosis
01/2022
1Cardiovascular Diseases (Cardiovascular Disease)
01/2022
1Cardiomegaly (Heart Hypertrophy)
01/2022
1Atherosclerosis
10/2021
1Cicatrix (Scar)
01/2021
1Neoplasms (Cancer)
01/2021
1Chronic Renal Insufficiency
01/2020
1Acute Kidney Injury (Acute Renal Failure)
01/2020
1Rheumatoid Arthritis
01/2019
1Pulmonary Fibrosis (Fibrosing Alveolitis)
01/2019
1Inflammation (Inflammations)
01/2019
1Pulmonary Arterial Hypertension
12/2018
1Hypoxia (Hypoxemia)
12/2018
1Pulmonary Hypertension
12/2018
1Arthritis (Polyarthritis)
12/2018
1Familial Primary Pulmonary Hypertension
01/2016
1Cardiotoxicity
12/2015
1Pathologic Processes
05/2013
1Wounds and Injuries (Trauma)
01/2013
1Contracture
09/2012
1Heart Valve Diseases (Valvular Heart Disease)
11/2011
1Carcinoid Heart Disease
11/2011
1Ventricular Remodeling
06/2007
1Infarction (Infarctions)
06/2007

Drug/Important Bio-Agent (IBA)

7osteoblast cadherinIBA
10/2021 - 01/2013
6Pharmaceutical PreparationsIBA
01/2022 - 04/2014
5Proteins (Proteins, Gene)FDA Link
01/2022 - 05/2015
45-HT2B Serotonin ReceptorIBA
01/2021 - 01/2016
2CollagenIBA
01/2021 - 09/2012
2Serotonin (5 Hydroxytryptamine)IBA
01/2020 - 11/2011
2CateninsIBA
01/2020 - 06/2017
2CytokinesIBA
12/2018 - 05/2013
1TalinIBA
01/2022
1Angiotensin IIIBA
01/2022
1CholesterolIBA
01/2022
1Therapeutic UsesIBA
01/2021
1Glucose (Dextrose)FDA LinkGeneric
01/2021
1Glutamine (L-Glutamine)FDA Link
01/2021
1MicroRNAs (MicroRNA)IBA
01/2020
1FenfluramineIBA
01/2020
1Long Noncoding RNAIBA
10/2019
1Naproxen (Naprosyn)FDA LinkGeneric
04/2019
1Celecoxib (Celebrex)FDA Link
04/2019
1Cyclooxygenase 2 Inhibitors (COX-2 Inhibitors)IBA
04/2019
1Ibuprofen (Motrin)FDA LinkGeneric
04/2019
1Interleukin-6 (Interleukin 6)IBA
01/2019
1Diphtheria ToxinIBA
12/2018
1RNA (Ribonucleic Acid)IBA
12/2018
1Semaxinib (SU5416)IBA
12/2018
1TamoxifenFDA LinkGeneric
12/2018
1Biological ProductsIBA
12/2018
1Bleomycin (Blenoxane)FDA LinkGeneric
06/2017
1IntegrinsIBA
05/2015
1Cadherins (E-Cadherin)IBA
05/2015
1Transforming Growth Factors (Transforming Growth Factor)IBA
01/2013
1Serotonin ReceptorsIBA
11/2011
1Urea (Carbamide)FDA LinkGeneric
06/2007
1PolyestersIBA
06/2007
1salicylhydroxamic acid (SHAM)IBA
06/2007
1Urethane (Ethyl Carbamate)IBA
06/2007

Therapy/Procedure

4Therapeutics
12/2021 - 09/2012
2Radiofrequency Ablation
03/2014 - 09/2012
2Catheters
03/2014 - 09/2012
1Ovariectomy (Oophorectomy)
01/2022